Layout of a bathroom is partially dependent on waste water tank configuration. Mine run side-to-side with the deep end of the sump on the driver's side. I therefore put the toilet on the driver's side (over the deep end of the sump), with the shower adjacent to the toilet.
The vanity & a linen closet are on the passenger side. The bathroom has pocket doors front and rear so someone in the bedroom can have access (and privicy) or with the rear door closed, it can be used by someone bunking in the front.
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