I think it would be great with....
** 22.5's lightweight rims
** properly geared
** a tuned Power Stroke 6.7 and an 6 speed auto w/ OD
I would love to see one E550 with an aerodynamic style box like Road-trek or Pleasure Way etc.
**Mod some big storage units simalar to the first img down nearly to the ground and smooth out the whole bottom of those boxes with sheeting.
** nice aero bumper from a conversion van.
The whole thing weighing in at 13-14K it would be a cool one of a kind jelly burnin road trip rig